Study active · Foundation for Women's Cancer

Knowledge that can protect your entire family.

IGNITE-TX is a free research study helping families with Hereditary Breast and Ovarian Cancer (HBOC) or Lynch syndrome understand their genetic risk, share results, and access the right support.

IRB Approved Free to join
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Funded by Foundation for Women's Cancer Prevent Cancer Foundation American Cancer Society
Free
No cost to participate
TX
Nationwide study
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About IGNITE-TX

A study that helps families understand hereditary cancer risk.

The IGNITE-TX Study is a clinical trial designed to improve genetic testing among families affected by Hereditary Breast and Ovarian Cancer (HBOC) syndrome and Lynch syndrome. This research addresses a significant gap in care identified by the National Comprehensive Cancer Network (NCCN).

Today, fewer than 50% of at-risk relatives complete cascade genetic testing. This study seeks to understand and improve those rates — protecting more families through early knowledge.

Learn more about us
Why join the study

Three reasons to participate

Understand hereditary cancer risk

Learn more about hereditary cancer syndromes such as HBOC or Lynch syndrome and how they may affect families.

Support your family

Learn how genetic information may help relatives better understand inherited cancer risk and available resources.

Support throughout participation

Our study team is available to answer questions and provide support throughout the study experience. Participation is voluntary.

Voices from the study

“This study presents a unique opportunity to enhance genetic testing”

— IGNITE-TX Research Team

“Genes don’t define us but they can guide our choices”

— Study participant
Watch our overview
3 min · English & Español
Research team

The people behind the study

Full team
JR
J. Alejandro Rauh-Hain, MD, MPH
Gynecologic Oncologist
Department of Gynecologic Oncology and Reproductive Medicine, MD Anderson Cancer Center
Principal Investigator
NA
Nuria Agusti, MD
Research Coordinator · Study Manager
UCLA Jonsson Comprehensive Cancer Center
Study Manager
SL
Sayoni Lahiri, MS, CGC
Certified Genetic Counselor
Simmons Comprehensive Cancer Center, UT Southwestern Medical Center
Genetic Counselor
Free to participate

Ready to see if you are eligible?

If you or a family member have been diagnosed with HBOC or Lynch syndrome, we'd like to hear from you. Enrollment takes just a few minutes and is completely free.