A study built on knowledge, care, and family.
The IGNITE-TX Study is a clinical trial investigating how to better support families diagnosed with Hereditary Breast and Ovarian Cancer (HBOC) syndrome or Lynch syndrome (LS).
Both conditions are caused by inherited gene mutations that significantly increase cancer risk — not just for the person diagnosed, but for their entire family.
Through IGNITE-TX, we're learning how patients can better understand their genetic test results, share this life-changing information with relatives, and access the resources they need to take action.
Participation is completely free. Our team is here to support you at every step.
"Being aware of our genetic risks empowers us to make informed decisions — for ourselves and for the people we love."
Why genetic testing matters
Understanding your genetic risk isn't just about you — it's about everyone who shares your DNA.
When someone is diagnosed with HBOC or Lynch syndrome, their close relatives may carry the same gene mutations and face elevated cancer risks without knowing it. Yet across the country, fewer than 50% of at-risk relatives ever pursue genetic testing.
IGNITE-TX exists to change that. By helping families navigate genetic information together, we can turn awareness into prevention — and science into care.
Our dedicated support team is available to address any questions about genetic results or the study itself, at every step of the process.
What we're working to achieve
The primary objectives of the IGNITE-TX Study are to help families understand their cancer risk linked to HBOC and Lynch syndrome, share genetic testing results with at-risk relatives, and connect participants with essential resources for those considering testing
Both HBOC and Lynch syndrome increase the likelihood of cancer in men and women. This trial presents a unique opportunity to expand access to genetic knowledge for families across Texas — and make early prevention a reality for more people.
The people behind the study
Have questions about the study?
Our team is here to help. Reach out anytime — we're happy to answer any questions about eligibility, the study process, or genetic testing.
Or email us at ignitestudy@mdanderson.org